Context
Developed during international collaboration to improve reproducible imaging readouts in ALS inflammation models.
Research note
ALS Neuroinflammation Imaging Workflow
Raw image and processed view
A simple comparison of microscopy signal and processed segmentation output.
Annotated image
Highlighted points connect image regions to interpretation notes.
Closer view
A closer look at the processed microscopy image.
Process
1. Preparation
Electron microscopy sample preparation for stable cross-lab comparability.
2. Imaging
Acquisition across modalities to capture morphology and inflammation context.
3. Overlay
Alignment and layered interpretation of multi-modal outputs.
4. Reporting
Built communication-ready visuals for collaborative interpretation.